Revision Notes on: Inheritance and Variation - GSEB SCIENCE HUB

 Revision Notes on Inheritance and Variation






Mendel’s Law of Inheritance


(1) Mendelism means experiments performed by Mendel on genetics.

(2) Mendel’s experiment involved 4 steps as selection, hybridization, selfing and calculations. His results led to the formation of laws of genetics later.

(3) Mendel performed monohybrid and dihybrid crosses and gave three principles of inheritance.

(4) Mendel’s three principles of inheritance are:
(i) Law of dominance
(ii) Law of segregation or law of purity of gametes
(iii) Law of independent assortment

(5) Law of Dominance: The dominant characters are expressed when factors are in heterozygous condition.

(6) The recessive characters are only expressed in homozygous conditions. The characters never blend in heterozygous condition. A recessive character that was not expressed in heterozygous condition may be expressed again when it becomes homozygous.

(7) Law/Principle of segregation states that when a pair of contrasting factor or gene is brought together in a hybrid, these factors do not blend or mix up but simply associate themselves and remain together and separate at the time of gamete formation.

(8) Principle of independent assortment states that genes of different characters located in different pairs of chromosomes are independent of one another in this segregation during gamete formation.

(9) Test Cross: A cross between F1 hybrid (Aa) and its homozygous recessive parent (aa) is called Test Cross. This cross is called test cross because it helps to find out whether the given dominant phenotype is homozygous or heterozygous.

(10) Monohybrid cross: When we consider the inheritance of one character at a time in a cross, this is called monohybrid cross.

(11) Dihybrid Cross: A cross made to study the inheritance of two pairs of contrasting traits.


Exceptions of Conclusions of Mendel

Incomplete Dominance

(1) When neither of the alleles of a character is completely dominant over the other and the F1 hybrid is intermediate between the two parents, the phenomenon is called incomplete dominance.

(2) Incomplete dominance was first discovered by Correns in Mirabilis jalapa. The plant is called as 4’O clock plant or ‘Gul-e-Bans’.  Homozygous red (RR) flowered variety of the plant was crossed with white (rr) flowered variety.  F1 offspring had pink flowers (Rr).  This is called incomplete dominance.

(3) Incomplete dominance is also known to occur in snapdragon.  The phenotypic ratio and genotypic ratio in F2 generation in case of incomplete dominance is 1:2:1.

Co-dominance

(1) In co-dominance both the gene expressed for a particular character in F1 hybrid progeny. There is no blending of characters, whereas both the characters are expressed equally.

(2) Co-dominance is seen in animals for coat colour. When a black parent is crossed with white parent, a roan color in F1 progeny is produced.

Sex determination:

(1) Fixing the sex of an individual as it begins life is called sex determination. The various genetically controlled sex-determination mechanisms have been classified into following categories

(2) Chromosomal theory of sex determination: The X-chromosome was first observed by German biologist, Henking in 1891 during the spermatogenesis in male bug and was described as X-body. The chromosome theory of sex determination was worked out by E.B. Wilson and Stevens (1902-1905).

(3) They named the X and Y chromosomes as sex-chromosomes or allosomes and other chromosomes of the cell as autosomes.

(4) Sex chromosomes carry genes for sex. X-chromosomes carries female determining genes and Y-chromosomes has male determining genes.

(5) The number of X and Y chromosomes determines the female or male sex of the individual, Autosomes carry genes for the somatic characters. These do not have any relation with the sex.

Sex Determination by chromosomes:
Those chromosomes which are involved in the determination of sex of an individual are called sex chromosomes while the other chromosomes are called autosomes.

1) XX – XY type:  In most insects including fruit fly Drosophila and mammals including human beings the females possess two homomorphic sex chromosomes, named XX.  The males contain two heteromorphic sex chromosomes, i.e., XY. Hence the males produce two types of gametes / sperms, either with X-chromosome or with Y-chromosome, so they are called Heterogamety.

2) ZZ – ZW type:  In birds and some reptiles, the males are represented as ZZ (homogamety) and females are ZW (heterogamety).

3)  XX – XO type:  In round worms and some insects, the females have two sex chromosomes, XX, while the males have only one sex chromosomes X. There is no second sex chromosome. Therefore, the males are designated as XO.  The females are homogametic because they produce only one type of eggs.  The males are heterogametic with half the male gametes carrying X-chromosome while the other half being devoid of it.

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